Impact Case Studies
Impact Case Studies
Six studies showing what changed as a result of the research — in practice, in policy and in patient care. Publication counts demonstrate activity; impact narratives demonstrate consequence, and ranking and accreditation bodies increasingly weight the latter.
Pharmacist-led deprescribing reduces unnecessary long-term acid suppression Clinical Pharmacy, Medication Safety & DeprescribingSDG 3
The problem
Long-term proton pump inhibitor use without a continuing indication is widespread in the region and is associated with avoidable adverse outcomes and cost.
The research
A pharmacist-led randomised controlled trial tested a structured deprescribing protocol against usual care in outpatients on long-term therapy.
The findings
The intervention arm showed a substantially higher rate of appropriate discontinuation at six months with no increase in symptom recurrence requiring re-initiation.
The impact
The protocol has been adopted into local outpatient pharmacy workflow and forms the basis of a regional stewardship guideline submission.
Targeting RAN GTPase opens a new route in treatment-resistant breast cancer Cancer Biology & Targeted TherapeuticsSDG 3SDG 9
The problem
Triple-negative breast cancer has limited targeted treatment options and poor outcomes once metastatic.
The research
Sustained laboratory work characterised RAN GTPase as a driver of metastatic behaviour and tested small-molecule and delivery-based approaches to inhibit it.
The findings
Inhibition reduced invasive capacity in cell and rodent models, with a defined therapeutic window identified.
The impact
The work underpins an active international collaboration and has attracted doctoral candidates to the University specifically for this programme.
Non-invasive cardiovascular phenotyping brings preclinical capability to the Northern Emirates Cardiometabolic & Endocrine HealthSDG 3SDG 9
The problem
Preclinical cardiovascular research in the region has depended on sending studies abroad, adding cost and delay.
The research
CARF established non-invasive ECG and blood pressure systems alongside ex vivo working heart perfusion, under full ethical and regulatory licensing.
The findings
The facility now supports reproducible cardiovascular disease modelling across multiple disease areas without terminal endpoints for monitoring.
The impact
External academic and industry users now access the facility under contract research and collaborative models, retaining regional research spend.
Simulation-based interprofessional training changes team behaviour in acute care Nursing, Health Workforce & Community HealthSDG 3SDG 4
The problem
Communication failure between professions is a leading contributor to preventable patient harm.
The research
Structured interprofessional simulation scenarios were delivered through SIDC to mixed medicine, nursing, pharmacy and dentistry cohorts.
The findings
Measured improvements in team communication and escalation behaviour were sustained at follow-up.
The impact
The model is embedded in curricula across all four colleges and is being offered to regional healthcare employers as continuing professional development.
Host-modulation therapy improves outcomes in chronic periodontitis Oral Health & Restorative SciencesSDG 3
The problem
Conventional mechanical therapy alone leaves a substantial proportion of patients with residual disease.
The research
A programme of clinical studies evaluated adjunctive host-modulation agents alongside standard periodontal treatment.
The findings
Adjunctive therapy produced measurable additional improvement in clinical attachment in defined patient subgroups.
The impact
Findings inform regional periodontal treatment protocols and have been incorporated into postgraduate dental teaching.
Molecular surveillance strengthens antimicrobial stewardship in the Northern Emirates Infection, Microbiome & Antimicrobial ResistanceSDG 3
The problem
Resistance patterns in the region were poorly characterised, limiting the precision of empirical prescribing guidance.
The research
TMRC established molecular characterisation of resistant isolates in partnership with regional diagnostic laboratories.
The findings
Distinct local resistance profiles were identified that differ from those assumed by imported guidelines.
The impact
Findings feed into local empirical prescribing guidance and national AMR surveillance reporting.
How each case study is told
Each case study follows the same structure — the problem, the research, the findings, the impact and what happens next — at roughly 600 words. A consistent structure keeps them comparable and keeps authors disciplined. SDG tagging additionally supplies structured evidence for impact-focused ranking submissions.
- The problem
The health or education question the work set out to address.
- The research
What was studied, and how.
- The findings
What the work showed.
- The impact
What changed in practice, policy or patient care.
- The goals
The UN Sustainable Development Goals the work serves.